ABSTRACT
<p><b>OBJECTIVE</b>To investigate an effective method for the correction of the narrow nostril secondary to cleft lip.</p><p><b>METHODS</b>A "bird wing shape" incision was made on the nasal tip to form a "W-shape" flap for repairing the nasal deformities secondary to cleft lip, especially for the cases with narrow nostril.</p><p><b>RESULTS</b>Twenty-eight patients were treated with this method. All the cases achieved a symmetry shape of nasal ala, nostril, nasal columella and a normal height of nasal tip except for 2 cases with malformation at nasal tip who achieved improvement after reoperation. 21 cases were followed up for 6-12 months with good cosmetic result and no recurrence.</p><p><b>CONCLUSIONS</b>"W-shape" flap at the nasal tip is an ideal way for the correction of mild to moderate narrow nostril deformity secondary to cleft lip.</p>
Subject(s)
Adolescent , Adult , Female , Humans , Male , Young Adult , Cleft Lip , General Surgery , Nose , Congenital Abnormalities , General Surgery , Nose Deformities, Acquired , General Surgery , Rhinoplasty , Methods , Skin Transplantation , Surgical FlapsABSTRACT
<p><b>OBJECTIVE</b>To investigate the effect of a modified technique for repairing secondary defect of unilateral cleft lip.</p><p><b>METHODS</b>The incision line was designed along the oral-nasal contour line. The lateral crus of nasal alar were rotated and repositioned in order to reconstruct the nasal sill and base. V-Y plasty was performed with a muco-cartilage flap inside the nasal cavity to reset the alar cartilage backwards and correct the nasal deformity.</p><p><b>RESULTS</b>Satisfactory results were achieved in all 69 patients with this modified technique. The post-operative scar was inconspicuous.</p><p><b>CONCLUSIONS</b>This modified technique with advantages of contour line incision and alar cartilage backward re-reposition is a good option for the repair of secondary defect of unilateral cleft lip.</p>
Subject(s)
Adolescent , Adult , Female , Humans , Male , Young Adult , Cleft Lip , General Surgery , Lip , Congenital Abnormalities , Nose , Congenital Abnormalities , Nose Deformities, Acquired , General Surgery , Plastic Surgery Procedures , MethodsABSTRACT
<p><b>OBJECTIVE</b>To explore the methods for repair of facial and cervical scars after burn.</p><p><b>METHODS</b>One hundred and two patients with facial and cervical scars as a result of burn injury were repaired by unilateral or bilateral deltopectoral flaps after expansion with pedicles. First, facial scars were excised and contractures were released to restore eye, mouth and nose to normal anatomical position. The facial scar flaps were overturned to join with the pedicles of deltopectoral flap for closing the wounds. The residual wounds were repaired by delayed flaps without pedicles 3 weeks later.</p><p><b>RESULTS</b>Among 102 patients, the flaps survived well in 94 cases, and blood supply insufficiency was found in distal end of unilateral flap in 7 cases (depigmentation after primary healing ). Necrosis of unilateral flap occurred in one patient, and it healed after skin grafting.</p><p><b>CONCLUSION</b>Expanded deltopectoral flap is efficacious procedure for repair of massive cervical and facial scars.</p>
Subject(s)
Adolescent , Adult , Child , Humans , Male , Young Adult , Burns , Cicatrix , General Surgery , Face , Pathology , Facial Injuries , Neck , Pathology , Plastic Surgery Procedures , Methods , Skin Transplantation , Methods , Surgical Flaps , ThoraxABSTRACT
<p><b>OBJECTIVE</b>To investigate the perioperation medication on the first patient who was operated facial allotransplantation, including immunosuppressive drug and adjunctive drug, so that to search a effective medication schedule to the patient operated facial allotransplantation.</p><p><b>METHODS</b>FK506, MMF, Prednisone and Zenapax was performed as immunosuppressive regiment in perioperative treatment; meanwhile, anti-infectives was administered to take precautions against all sorts of infections, such as bacterium, virus and fungus. Furthermore, all kinds of adjunctive drug, Losec, glucurolactone and so on, was administered to protect those function of stomach, liver, kidney and so on. Clinical observations were made on the signs and symptoms of graft survival or rejection, as well as immunological indexes were tested in laboratory. Biopsies of graft were also made at 30 d after operation. Side effect and complication of drug was monitored, in case the body suffered harm.</p><p><b>RESULTS</b>Facial allograft was survived, and the temperature and color of skin were normal. Swelling of tissue was gradually subsidise after 4 days, and recovered in a half month. The count and ratio between Th and Ts were normal, skin Biopsies of every time had no found of hyperacute or acute rejection, and side effect and complication of drug had no monitored.</p><p><b>CONCLUSIONS</b>The regiment of perioperation medication was successfully performed.</p>
Subject(s)
Adult , Humans , Male , Face , General Surgery , Immunosuppressive Agents , Therapeutic Uses , Tissue Transplantation , Methods , Transplantation, HomologousABSTRACT
<p><b>OBJECTIVE</b>To determine the change of P-selectin in avulsion-injured vessels.</p><p><b>METHODS</b>Different stretch forces of 60, 70, 80 and 90 g were applied to a vascular injury model. The expression changes of P-selectin were evaluated by RT-PCR.</p><p><b>RESULTS</b>The expression of P-selection mRNA in the injured vessels increased with the stretch force.</p><p><b>CONCLUSION</b>The result associated with our previous study indicated that P-selectin may be involved in thrombosis.</p>